Journal of Yeungnam Medical Science

Son Moon Shin

22 Articles

Causative organisms of neonatal sepsis.: Kyung Ah Kim, Son Moon Shin, Han Gu Moon, Young Hoon Park; Yeungnam Univ J Med. 1999;16(1):60-68. Published online June 30, 1999; DOI: https://doi.org/10.12701/yujm.1999.16.1.60

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A nationwide survey was conducted to investigate the annual occurrence rate of neonatal sepsis, maternal risk factor in neonatal sepsis, localized infection in neonate, causative organism in nosocomial infection and the most common causative organism in neonatal sepsis in Korea. Clinical and bacteriological data were collected from thirty seven neonatal units through retrospective review of the medical records of the newborn infants who were confirmed as neonatal sepsis by isolating organisms from blood culture during one year study period from January to December in 1997. 78,463 neonates were born at 37 hospital in 1997 and 20,869 neonates were admitted to the neonatal units. During this period, 772 episodes of neonatal sepsis were recorded in 517 neonates. The occurrence rate of neonatal sepsis was 0.73%(0~2.95%). Male to female ratio was 1.15:1 and 303 cases(42.1%) were born prematurely. The main pathogens of early onset sepsis were S. aureus(20%), S. epidermidis(14.4%) and coagulase negative Staphylococcus( 14.4%). Gram negative bacilli including Enterobacter spp (7.2%), E.coli(5.1%), Klepsiella(4.5%), Pseudomonas(3.7%) Enterobacter faecium(3.6%) constitute 24.1%. Only two cases of group B beta-hemolytic Streptococcus were isolated. Common obstetric factors were PROM(21.1%), difficulty delivery(18.7%), fetal tachycardia(5.3%), chorioamnionitis(4.9%), maternal fever(4.7%). The main pathogens of late-onset sepsis were S. aureus(22.3%), S. epidermidis(20.4%) and CONS(9.9%). There were 6 cases (1.0%) of Candida sepsis. Frequent focal infections accompanying sepsis were pneumonia(26.1%), urinary tract infection(10.5%), meningitis(8.2%), and arthritis(3.6%). S. epidermidis(22.0%) and S. aureus(21.7%) were also the most common pathogens in 373 nosocomial infection.

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Characteristics of Microorganisms Isolated from Blood Cultures at a University Hospital Located in an Island Region During 2003~2007
Sung Ha Kang, Young Ree Kim
Korean Journal of Clinical Microbiology.2008; 11(1): 11. CrossRef
Microorganisms Isolated from Blood Cultures and Their Antimicrobial Susceptibility Patterns At a University Hospital During 1994-2003
Eun-Mi Koh, Sang-Guk Lee, Chang Ki Kim, Myungsook Kim, Dongeun Yong, Kyungwon Lee, June Myung Kim, Dong Soo Kim, Yunsop Chong
Annals of Laboratory Medicine.2007; 27(4): 265. CrossRef

The Preventive Effect of Antenatal Administration of Ambroxol on the Neonatal Respiratory Distress Syndrome.: Eun Sil Lee, Kyung Ah Kim, Son Moon Shin, Min Whan Koh, Tae Hyung Lee; Yeungnam Univ J Med. 1999;16(1):52-59. Published online June 30, 1999; DOI: https://doi.org/10.12701/yujm.1999.16.1.52

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Abstract PDF: This study was conducted to evaluate the effect of antenatal ambroxol administration to the mothers who were imminent preterm delivery on preventing the neonatal respiratory distress syndrome. Forty-two preterm newborn infants who were delivered at Yeungnam University Hospital from January 1996 to December 1997 were divided into two groups, twenty-one ambroxol-treated group and twenty-one control group. Six cases of respiratory distress syndromes developed from 21 ambroxol-treated infants. but thirteen cases of RDS developed from 21 control infants. It indicated significant reduction of occurrence of RDS by antenatal administration of ambroxol (p<0.05). There were no differences in the occurrence of adverse effects of ambroxol in mothers between two groups, ambroxol-treated and control groups. There was also no difference between pre- and post-treatment hematologic and biochemical parameters in ambroxol-treated group. In conclusion, when premature delivery is expected, administration of ambroxol before delivery enhances lung maturation in premature newborn infants and prevents the occurrence of respiratory distress syndromes without significant adverse effects.

A case of incontinentia pigmenti developed in a male newborn infant.: Min Jeong Cho, Son Moon Shin, Han Ku Moon; Yeungnam Univ J Med. 1998;15(2):381-390. Published online December 31, 1998; DOI: https://doi.org/10.12701/yujm.1998.15.2.381

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Incontinentia pigmenti is characterized by irregular linear blisters with erythematous lesions which are developed from birth or later, verrucous papules on the extremities which are noted after a few weeks or months, and the appearnace of streaks, spots and swirls of hyperpigmentation. This disorder is known as a systemic disorder caused by a defect at the developmental stage of organs originated from ectoderm or mesoderm. We experienced an incontinentia pigmenti in a male newborn infant who did not have any family history and had cutaneous lesions, which were in bullous and verucous stages, ophthalmic problems, and neurologic abnormalities.

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Case of a Male Newborn with Incontinentia Pigmenti Initially Misdiagnosed as a Recurrent Skin Infection
Sang Ho Park, Kyung-Hwa Nam, Yo Han Ho
Neonatal Medicine.2020; 27(3): 141. CrossRef

A Study on the Bone Density in Newborn Infants: Difference of the Bone Mineral Density according to the Gestational Age and the Birth Weight.: Eun Sil Lee, Son Moon Shin, Han Ku Moon, Yong Hoon Park, Kwang Hae Choi; Yeungnam Univ J Med. 1997;14(2):383-392. Published online December 31, 1997; DOI: https://doi.org/10.12701/yujm.1997.14.2.383

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Abstract PDF: To study the differenced of bone mineral density according to the gestational ages and the birth weight and get a reference data for the diagnosis of metabolic bone diseases in the newborn infants, bone mineral densities of the lumbar vertebrae were measured in fifty-three newborn infants bone at Yeungnam University Hospital from March 1, 1995 to February 28, 1997, whose gestational ages were between 28+3 and 41+3 weeks and who had no intrauterine growth retardation, using dual energy X-ray absorptiometry (X-R 26, Norland, USA) within seven days of life. 1. There was no sexual difference in bone mineral density. The bone density increased significantly as gestational age increased from 0.149+/-0.009 g/cm2 at 28-30wks to 0.229+/-0.034 g/cm2 at 39-41wks of gestational age (p<0.05), but there was no significant difference between bone mineral density at 33-34wks and 35-36wks. There was positive linear correlation netween gestational age and bone mineral density (Y=7.5?10-3X-0.082, r=0.7018, p<0.001). 2. The bone mineral density increased significantly as the birth weight increased from 0.158+/-0.020 g/cm2 in 1,000-1,499 g to 0.251+/-0.021 g/cm2 in 3,500-4,000 g of the birth weight (p<0.05), but there was no significant difference between bone mineral densities in 1,000-1,499 g and 1,500-1,999 g of the birth weight. There was positive linear correlation between the birth weight and the bone mineral density (Y=3.9?10-5X+0.093, r=0.7296, p<0.001). There were positive correlations between the bone mineral density and gestational age, and between the bone mineral density and the birth weight. It can be used as a reference data for the further study on the bone mineral metabolism in the newborn infants including preterm babies.

A Survey on the Knowledge and Attitudes of Women in Taegu toward Weaning Diet for Infants.: Kyung Ah Kim, Eun Sil Lee, Young Hwan Lee, Son Moon Shin, Kwang Hae Choi; Yeungnam Univ J Med. 1997;14(2):370-382. Published online December 31, 1997; DOI: https://doi.org/10.12701/yujm.1997.14.2.370

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Successful Weaning is very important to provide adequate nutrients for nomal growth and to induce a good diet habit. We conducted a survey on the Knowledge and attitudes of women who live in Taegu toward weaning in infants, to figure out how much they know about weaning diet for the infants, which source they prefer to get the information about weaning diet, whether their knowledge affect their practice about weaning in infants, and the most effective way to educate them. A survey was conducted with the prepared questionnaire on women who responded all the residential area and market place, and those who visited Department of Pediatrics, Yeungnam University hospital from July 25 to September 15, 1997. Statistical analysis was done with student t-test and ANOVA using SPSS program. Among total 303 responders, those who aged between 30 and 39 year were 37.2%. Scores for the six questions about weaning policy showed highest in the age group between30 and 39 years. Higher score was recorded in the more educated group, in those who get informations about weaning diet from books, magazines and pediatricians. The majority of the responders had wrong concepts, such as feeding weaning diet using bottle(69.1%), feeding mixed with formula in the same bottle(64.5%), addition of salt(68.4%), Those who had higher educational level preferred books, magazines rather than neighbors or mother to get informations about weaning diet. Those who preferred books or magazines started weaning, stopped bottle feeding, and used spoon earlier, and their children had unbalanced diet habits less frequently. Home-made food was most frequently, and commercial products were used less frequntly. Those who ewre employed preferred home-made good rather than commercial products, it may be caused by the difference of the educational backgrounds from those of the unemployed. In conclusion, most responders ask neighbors and mother to get informations about weaning, and the incorrect knowledge from them colud cause inadquate weaning practice and induced bad diet habit in their children. We have to find the reasons why they did not refer books or magazines frequently, and the way to resolve the problem.

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Market Segmentation for Commercial Baby Food by Food-Related Lifestyle of Korean Housewives
Bang-jin Bark, Wan-Soo Hong
Korean Journal of Food & Cookery Science.2017; 33(4): 452. CrossRef

Effect of Low Lactose Special Formula (MF-1)for the Treatment of Acute Diarrhea in Infants.: Oh Hyouk Kwon, Sang Duk Kim, Kyeung A Kim, Son Moon Shin; Yeungnam Univ J Med. 1996;13(2):251-260. Published online December 31, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.2.251

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Abstract PDF: To evaluate the effect of low lactose special formula (MF-1) for the treatment of acute diarrhea, we studied thirty nine infants who were admitted with acute diarrhea to the Department of Pediatics Yeungnam University Hospital. 39 infants of under 6 months of age who had been fed on formula feeds were randomly allocated to receive either a diluted regular formula milk or a low lactose special formula. Each infant received intravenous rehydration during fasting for 6-12 hours. Group 1 (n=15) was fed half strength of regular formula (80-100 cc/kg/day) for the first 24 hours, three quarters strength formula (100-120 cc/kg/day) for the next 24 hours, and continued feeding with the full strength regular formula milk. Group 2 (n=24), who fed the same amount of milk as Group 1, continued feeding with the full strength low lactose special formula from the start of feeding. Male to female sex ratio was 1.6 to 1. The characteristics of infants on admission were comparable in the age, the duration of diarrhea and the stool frequency before admission, the degree of dehydration. There were no significant differences in the duration of hospitalization, changes in stool weight and stool frequency after admission between two groups (p>0.05). The Body weight and skin fold thickness were increased in group 2 who fed low lactose formula, but those who fed diluted regular formula showed reduction of body weight and skin fold (64.2±51.4 g vs -11.4±52.2 g, 0.6±0.8 mm vs -0.1±0.3 mm respectively) during hospitalization (p<0.05). We conclude that low lactose special formula milk can be recommended instead of diluted regular formula for acute diarrhea treatment in infants

Infantile Hypertrophic Pyloric Stenosis.: Young Soo Huh, Gyu Rag Kim, Son Moon Shin; Yeungnam Univ J Med. 1996;13(2):199-210. Published online December 31, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.2.199

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Abstract PDF: Infantile hypertrophic pyloric stenosis(IHPS), which occurs three of 1,000 live births, is a major cause of 1 nonbilious vomiting of early infancy but its etiology and pathogenesis are still obscure. The operation of pyloromyotomy as described by Ramstedt in 1912 remains the standard of care for the treatment of IHPS. From January 1993 to October 1996, 35 infants with IHPS were surgically treated and the following results were obtained. 1. Thirty-five patients comprised 32 males and 3 females, and the ratio of male to female was 10.7:1. 2. The most prevalent age group was between 2 weeks and 8 weeks. 3. Of 35 infants, first born babies were 23 cases(65.7%). 4. Breast feeding was in 23 cases(65.7%). 5. The body weight percentile at admission was lower than 50 percentile in all 35 cases. 11. A total of seven associated anomalies were noted in six patients. 12. All 35 cases were treated with Fredet-Ramstedt pyloromyotomy. 13. There were postoperative complications of wound infection in 2 cases. Intermittent nonprojectile vomiting was presented in 8 cases(22.9%) after operation, but one of them was relieved in 13 days and the rest were relieved within one week by adjustment of oral intake.

Neonatal Transport.: Son Moon Shin; Yeungnam Univ J Med. 1996;13(2):192-198. Published online December 31, 1996; DOI: https://doi.org/10.12701/yujm.1996.13.2.192

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Abstract PDF: No abstract available.

The Effect of the Local Anesthetic Cream in Alleviating Pain form Vaccination.: Sang Duk Kim, Son Moon Shin, Yong Hoon Park; Yeungnam Univ J Med. 1994;11(2):270-276. Published online December 31, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.2.270

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To evaluate the effect of a new topical anesthetic cream (EMLA : Eutectic mixture of local anesthetics) on reducing pain associated with DPT vaccination, we conducted a clinical observation on eighty infants who were brought to well baby clinic of Yeungnam University Hospital for DPT vaccination. 80 Infants, who were between 2 months and 8 months in age, were divided into two groups. EMLA treated group and control group. Male to femle sex ratio was 1.4 to 1. EMLA cream was applied 60 minutes before DPT vaccination, the effect of reducing pain was assessed by using McGrath's face scale, Oucher pain scale and modified behavioral pain scale (MBPS) and also evaluated by measuring the duration and time of crying (the time of the first crying after iniection, duration of the first crying, total duration of crying). The scores of those scales were lower in EMLA treated group than in control group significantly (P<0.01 in McGrath's face scale. MBPS and p<0.05 in Oucher pain scale). There was no difference in the time of the first crying after vaccination in both groups. The duration of the first crying was shorter in EMLA treated group than control group of crying was also shorter in EMLA treated group (EMLA treated group 9.0±12.5 sec, p<0.05). Transient skin erythema was noted in 5 infants after EMLA application, but no other adverse effects were observed. We conclude that the application of EMLA cream before vaccination seems to be an effective and safe way to reduce the pain from vaccination, but it takes usually 60 minutes to get the anesthetic effect of EMLA and it is expensive, so EMLA cream can not be recommended in routine vaccination in infants now.

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Effect of vapocoolant spray and EMLA cream upon DPT vaccination pain in infants
Gunja Jang, Eunyoung Jeon, Eunsil Lee
Journal of the Korean Data and Information Science Society.2014; 25(4): 705. CrossRef
The effects of EMLA cream on pain responses of preschoolers
Se Na Ahn, Joohyun Lee, Hae Won Kim, Sook Bin Im, Byung Sun Cho, Hye Young Ahn
Open Journal of Nursing.2013; 03(08): 1. CrossRef

Measurements of Mid-arm Circumference(MAC) and Mid-arm Circumference/Head Circumference(MAC/HC) Ratio as Indices of Nutritional Status in Newborn Infants.: Jae Jun Lee, Kyung Ah Lee, Young Hwan Lee, Son Moon Shin; Yeungnam Univ J Med. 1994;11(1):160-166. Published online June 30, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.1.160

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Abstract PDF: Mid-arm circumference and mid-arm circumference/head circumference ratio(MAC/HC) were measured in 207 AGA(appropriate for gestational age) infants delivered at 26 to 42 weeks of gestation from January 1990 to December 1993 in Yeungnam University Hospital, Taegu, Korea. There were linear relationships between MACs and MAC/HC ratios and gestational age(MAC : y=03181x -2.2069, r=0.81, p<0.001 ; MAC/HC ratio : y=0.049x+0.1128, r=0.62, ; < 0.001). Using standard curves of MAC and MAC/HC ratio according to the gestational age, measurement of MAC or MAC/HC ratio can be a noninvasive, simple method to evaluate the intrauterine growth of newborn infants and the nutritional status of growing premature infants.

Effect of Recombinant Human Erythropoietin in the Anemia of Prematurity : a Pilot Study.: Kyung Ah Lee, Son Moon Shin, Yong Hoon Park, Jeong Ok Hah; Yeungnam Univ J Med. 1994;11(1):115-126. Published online June 30, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.1.115

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Abstract PDF: The recent availability of recombinant human erythropoietin has opened new perspectives in the management of a variety of anemias. Clinical trials have been initiated in several countries using different approaches and methodology. We randomly assigned twelve premature infants(gestational age < 32 week) at high risk of requiring erythrocyte transfusion for anemia of prematurity with either subcutaneous recombinant human erythropoietin or a placebo. Treatment with rHuEPO was initiated at a dose of 100 units/kg day for 3 days a week. All patients were given supplemental oral iron therapy at a dose of 3 mg/kg per day, as tolerated and oral vitamin E at a dose of 25 units per day. Treated and control babies did not differ with respect to weight, hematocrit, overall mean reticulocyte count or rate of growth respectively. However, reticulocyte counts increased earlier in patients given rHuEPO. We conclude that rHuEPO administration is safe and feasible at the dose studied.

Congenital Ileal Atresia in Newborn.: Young Soo Heo, Chang Sig Kim, Son Moon Shin; Yeungnam Univ J Med. 1994;11(1):35-41. Published online June 30, 1994; DOI: https://doi.org/10.12701/yujm.1994.11.1.35

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Abstract PDF: Newborns with ileal atresia frequently present with abdominal distension, bilious vomiting, and failure to pass meconium. Diagnosis is usually established on plain x-ray of the abdomen by the findings of distended small bowel loops and air-fluid levels. In the period of October 1988 to February 1994, 8 patients with congenital ileal atresia were operated and the following results were obtained. 1. Eight patients were comprise of 4 males and 4 females, the ratio of male and female was 1 : 1. 2. Six patients(75%) had been admitted to our hospital during three days of life. 3. Congenital ileal atresia was in 8 cases : Type I in two(25%), Type II in two(25%), Type III a in three(37.5%), Type III b in one(12.5%). 4. There was one premature patient who was small for gestational age. 5. Overall, abdominal distension and bilious vomiting occurring in seven patients, were frequent presenting complaints. 6. Diagnosis was possible with clinical symptom and simple abdomen. 7. Operative treatment was undertaken as soon as the diagnosis was made. In seven cases a primary end-to-end anastomosis was performed after resection of dilated proximal loop. 8. A total of four associated congenital anomalies were found in one patient. 9. Postoperative complications occurred in three cases(37.5%).

Treatment of PDA in premature newborns with mefenamic acid.: Jae Joon Lee, Young Hwan Lee, Son Moon Shin; Yeungnam Univ J Med. 1993;10(2):506-511. Published online December 31, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.2.506

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This study was conducted to examine the effect of mefenamic acid for treatment of PDA in premature newborns. Ductus arteriosus is reopened by locally produced prostaglandin E2 in a premature newborn during hypoxia. Mefenamic acid is one of non-steroidal antiinflammatory drugs acting by inhibition of cyclo-oxygenase in the prostaglandin synthesis pathway. For three premature newborns with PDA, we administered mefenamic acid and evaluated them with echocardiography to study the effect of mefenmic acid for closure of PDA. In all three babies, ductus arteriosus was closed successfully. We feel that mefenamic acid is safe and effective medication for treatment of PDA in premature newborns, but further-study need to be conducted with larger numbers of cases to confirm this effect.

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Efficacy of oral mefenamic acid versus paracetamol as a prophylactic analgesic for needle pain in children receiving vaccination: a three-arm, parallel, triple-blind, placebo-controlled MAP VaC randomized controlled trial
Rachna Pasi, Thirunavukkarasu Arun Babu, Vinoth Kumar Kallidoss
Therapeutic Advances in Vaccines and Immunotherapy.2023;[Epub] CrossRef

A study of bone mineral density of lumbar spine by dual energy x-ray absorptiometry (DEXA) in children.: Chur Woo You, Son Moon Shin, Yong Hoon Park, Son Yong Kim; Yeungnam Univ J Med. 1993;10(2):369-379. Published online December 31, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.2.369

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Abstract PDF: The bone mineral density(BMD) of the lumbar spine (L2L4) was measured by using dual energy x-ray absorptiometry(Norland M6 DEXA) in 80 children aged between 2months and 15years (group I:2monthlyears, group 2: 1year5years, group3:6years10years, group4*: 11years15years). The correlation coefficient of BMD with age, body weight, height and Tanner stage were 0.696, 0.693, 0.717 and 0.636 respectively. There were sigificant difference. in BMD(g/cm2) between-group 1(BMD : 0.335 0.175) and group 2(BMD : 0.627 0.200), and group 3(BMD : 0.714 0.189) and group.4(BMD : 0. 8730.163) (P<0.05). There was no significant difference of BMD between boys and girls(P<0.05). BMD also increased significantly with development of Tanner stages(Tanner stage 1 : 0.547 0.234, Tanner stage 2 : 0.783 0.136, Tanner stage 3 : 0.998 0.080) (P<0.05). These data indicate that the BMD was correlated with age, body weight, height and Tanner stage significantly and BMD increased significantly during growth spurt occured in 1 to 4years of age and puberty.

Meaning of anti hepatitis C virus antibody detection in patients treated with intravenous immunoglobulin: Myong Gyun Lee, Young Hwan Lee, Son Moon Shin, Jeong Ok Hah; Yeungnam Univ J Med. 1993;10(2):306-312. Published online December 31, 1993; DOI: https://doi.org/10.12701/yujm.1993.10.2.306

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Abstract PDF: To evaluate the meaning of anti-HCV detection in patients treated with IVIG, serum levels of aspartate aminotranstferase(AST), alanine aminotransterase(ALT), HCV Ab titer were measured after treatment with IVIG in 36 patients diagnised of Kawasaki disease or neonatal sepsis. Also polymerase chain reaction (PCR) for the detection of HCV was done in 8 patients with persistent HCV Ab positivity at 3 months after IVIG treatment. The results were as follows 1) HCV Ab was positive in all 36 patients at 1 week after IVIG treatment, but in only 8 cases it was positive at 3 months after IVIG treatment. 2) AST, ALT were elevated in 9 cases at 1 week after IVIG treatment, but they were normalized in all cases at 3 months after IVIG treatment. 3) PCR for the detection of HCV was done in 8 patients with persistent HCV Ab positivity at 3 months after IVIG treatment, but HCV was not isolated in any cases. These results suggested that detection of anti-HCV was merely transitory phenominon of HCV Ab transmission, did not show any evidence of HCV infection due to HCV transmission.

A study of cisplatin nephrotoxicity.: Young Hee Hwang, Kyoung A Lee, Son Moon Shin, Young Hoon Park, Jeong Ok Hah, Chun Dong Kim, Young Hwan Lee; Yeungnam Univ J Med. 1992;9(2):327-333. Published online December 31, 1992; DOI: https://doi.org/10.12701/yujm.1992.9.2.327

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Abstract PDF: To evaluate the nephrotoxicity of cisplatin, serum levels of sodium, potassium, chloride, calcium, phosphorous, magnesium, BUN, creatinine and creatinine clearance were measured before and after administration of cisplatin in 18 cases of patients with malignant neoplasm. The results were as follows: 1) Serum calcium, magnesium, potassium and BUN levels were changed after cisplatin administration, but those changes were not statistically significant. 2) The mean value of creatinine clearance was not decreased significantly after treatment with cisplatin. 3) Acute renal failure was developed in one case, and four cases of hypocalcemia, hypomagnesemia were also detected after administration of cisplatin.

Low volume peritoneal dialysis in newborns and infants.: Young Hoon Park, Soo Ho Ahn, Son Moon Shin, Jeong Ok Hah; Yeungnam Univ J Med. 1991;8(2):128-137. Published online December 31, 1991; DOI: https://doi.org/10.12701/yujm.1991.8.2.128

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Abstract PDF: Peritoneal dialysis has been widely considered to be the dialytic treatment of choice for acute renal failure in infants and young children, because the technique is simple, safe and easily adapted for these patients. Also peritoneal dialysis in infants might have more effective ultrafiltration and clearance than in adults. In certain circumstances associated with hemodynamic instability, ordinary volume peritoneal dialysis (30-50 ml/kg body weight per exchange) or hemodialysis may not be suitable unfortunately. But frequent cycled, low volume, high concentration peritoneal dialysis may be more available to manage the acute renal failure of newborns and infants. Seven infants underwent peritoneal dialysis for hemodynamically unstable acute renal failure with low exchange volume (14.2±4.2 ml/kg), short exchange time (30 to 45 minutes) and hypertonic glucose solution (4.25% dextrose). Age was 1.9±1.3 months and body weight was 4.6±1.6 kg. Etiology of acute renal failure was secondary to sepsis with or without shock (5 cases) and postcardiac operation (2 cases). Catheter was inserted percutaneously with pigtail catheter or Tenkhoff catheter by Seldinger method. Dialysate was commercially obtained Peritosol which contained sodium, chloride, potassium, magnesium, lactate and calcium. Net ultrafiltration (ml/min) showed no difference between low volume dialysis and control (0.27±0.09 versus 0.29±0.09). Blood BUN decreased from 95.7±37.5 to 75.7±25.9 mg/dl and blood pH increased from 7.122±0.048 to 7.326±0.063 after 24 hours of peritoneal dialysis. We experienced hyperglycemia which were controlled by insulin (2 episodes), leakage at the exit site (2), mild hyponatremia (1) and Escherichia coli peritonitis (1). Two children of low volume dialysis died despite the treatment. In our experience, low volume and high concentration peritoneal dialysis with frequent exchange may have sufficient ultrafiltration and clearance without significant complications in the certain risked acute renal failure of infants.

Three cases of meconium peritonitis.: Young Hwan Lee, Soo Ho Ahn, Son Moon Shin, Young Soo Huh; Yeungnam Univ J Med. 1991;8(1):191-197. Published online June 30, 1991; DOI: https://doi.org/10.12701/yujm.1991.8.1.191

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Abstract PDF: Meconium peritonitis is an aseptic peritonitis caused by spill of meconium in the abdominal cavity through one or several intestinal perforations which have taken place during intrauterine life or early neonatal life. We experienced three cases of meconium peritonitis with ileal perforation in two cases 1 day-old male neonate and 2 day-old male neonate, respectively, which had the chief complaint of vomiting and abdominal distension. Literatures are reviewed, briefly.

Incidence of the chlamydial conjunctivitis in the newborn period.: Son Moon Shin, Mi Wha Kang; Yeungnam Univ J Med. 1989;6(2):23-28. Published online December 31, 1989; DOI: https://doi.org/10.12701/yujm.1989.6.2.23

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Abstract PDF: After application of silver nitrate on every newborn, the incidence of gonococcal conjunctivitis was markedly decreased. But recently neonatal conjunctivitis due to chlamydial infection is increasing, so clinical observation was made on 26 newborn infants who showed eye discharge from June 1st to August 31st 1989. The results were as follows. 1. The incidence of chlamydial infection among neonatal conjunctivitis was 34.6%. 2. The most common age at diagnosis was 6-15days of life and there was no secual preponderance. 3. There was no significant difference on clinical symptoms between chlamydial conjunctivitis and other conjunctivitis. 4. Of 26 infants examined, 16 cases revealed no growth on routine bacterial culture. Of the organism cultured, P. aeruginosa was the most common agent (19.2%) and followed by S. aureus (11.5%) and S. epidermidis (7.6%). In one case of chlamydial conjunctivitis, there was concurrent S. aureus infections. 5. On this study, Giemsa stain did not give significant diagnostic aid of chlamydial conjunctivitis.

A Case of Conjoined Twins.: Mi Hwa Kang, Son Moon Shin, Jin Gon Jun, Mi Jin Kim, Hae Joo Nam, Sung Rim Kim, Jong Wook Kim; Yeungnam Univ J Med. 1988;5(2):255-261. Published online December 31, 1988; DOI: https://doi.org/10.12701/yujm.1988.5.2.255

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Abstract PDF: Conjoined twinning is a rare congenital malformation, accounting for 1% monozygotic twins. Conjoined twins result if twining is initiated after the embryonic disc and rudimentary amniotic sac have been formed and if division of the embryonic disc is incomplete. Recently we experienced a case of conjoined twins, dicephalus dipus dibrachius, who had died at 3 hours of life, and performed autopsy. Autopsy revealed a total duplication of the heads, spines up to sacrum, small bowels, thymus and lungs. Two hearts existed within a common pericardium.

A Clinical Observation on 55 Cases of Neonatal Sepsis.: Jae Hong Park, Son Moon Shin; Yeungnam Univ J Med. 1988;5(2):161-169. Published online December 31, 1988; DOI: https://doi.org/10.12701/yujm.1988.5.2.161

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Neonatal Sepsis is a frequent and important cause of morbidity and mortality in the neonatal period. This study was undertaken to observe the 55 cases of proven neonatal sepsis among 6,717 newborn infants under 4 weeks of age, admitted to the nursery of Yeungnam University Hospital from May 1, 1983 to April 30, 1988. We observed following results: 1. The morbidity rate of male (1.12%) was higher than that of female (0.44%) significantly (p<0.05). 2. The morbidity rate of prematurity (2.65%) was higher than that of full term (0.76%) significantly (p<0.05). 3. The incidence of perinatal obstetric complications in early onset neonatal sepsis was higher than that of late onset neonatal sepsis (38.5% vs 10.3%, p<0.05). 4. The common clinical manifestations were poor feeding (52.7%), jaundice (45.5%), diarrhea (30.9%) and irritability (30.9%). 5. Among the causative organism, gram positive organisms were predominated and Staphylococcus epidermidis was the most common organism. There was no difference in the causative organisms between early onset and late onset sepsis.

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Antioxidant and Anti-Hemolytic Effects of Human Breast Milk from Koreans
Jeong-Eun Lee, Eun-Ji Yi, Moochang Kook
Resources Science Research.2022; 4(2): 67. CrossRef

A Clinical Study on Low Birth Weight Infants.: Han Ku Moon, Jung Ok Kim, Jae Honng Park, Son Moon Shin, Jeong Ok Hah; Yeungnam Univ J Med. 1987;4(2):97-103. Published online December 31, 1987; DOI: https://doi.org/10.12701/yujm.1987.4.2.97

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Abstract PDF: Neonatal and obstetrical problems related to the low birth weight infants were evaluated by a retrospective review of the medical records of the 186 low birth weight infants born at Yeungnam University Hospital during 3 years and 8 months from May 1, 1983 to February 28, 1987. The results were as follows: 1. The incidence of the low birth weight infants was 4.98% among 3,803 live births. 2. Male to female ratio was 1.02:1. 3. The incidence of the low birth weight infants was lowest in mothers of 25 to 29 years, increased in mothers of 19 years of less and 30 to 39 years significantly. 4. There was no difference in the incidence of low birth weight infants between primiparous and multiparous mothers. 5. Common obstetrical complications associated with low weight infants were multiple pregnancy, toxemia and premature rupture of membrane in order of frequency. 6. Common neonatal problems in low birth weight infants were jaundice, idiopathic respiratory, distress syndrome, asphyxia and metabolic derangement such as hypocalcemia and hypoglycemia in order of frequency.

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